When discussing sustainable cannabis, talk typically leans toward water conservation or energy efficiency. But, there are several overlooked areas of cannabis cultivation that are desperately in need of a sustainability overhaul.

Consider, for example, how much biomass is required to make cannabinoid isolates. Or, have you ever wondered how many outdoor plants are discarded every day due to mold, heat stroke, or wind damage?

Selective breeding could hold the key to addressing some of these issues and developing more resilient, vigorous varieties.

Environmental Considerations

CEO of Trilogene Seeds Matt Haddad shared how his company works to solve these issues by breeding customized plant varieties. They analyze the grower’s outdoor environment and determine which varieties will perform the best in those conditions.

Haddad explains, “We work with farmers to find the right plants for their respective environments then bring the plants back to our facilities so we can do breeding to mimic those environments. Then the next year, we provide a superior product than the year before. That helps their quality, yield, pest resistance, and mold resistance.”

Outdoor growing environments vary by region. Some companies are selectively breeding varieties better suited to the unique climates in which they’re grown. Plants grown in humid regions are more susceptible to pests and mildew, so cultivating varieties that are resistant to those issues will ensure healthier, more robust crops.

Many cannabis flowers are dried and cured before going to market, but live products are crafted using flower that is taken fresh off the plant. The flavor and aromatic notes are robust and more closely resemble that of the live cannabis plant than other concentrates. This may be why live resin products are in such high demand in all adult-use cannabis markets. Consumers don’t just dab live resin, they are also buying live vape cartridges. According to statistics from the BDSA Green Edge platform, live resin captures a 22% share of California’s vape market.

Headspace Technology

Research-focused terpene company Eybna Technologies noticed the market’s natural preference for live resin and sought to understand why these products were more desirable to the consumer. To do this, the terpene profile of a few cannabis plants were studied at three phases. The data was collected from the plant using the company’s proprietary Headspace technology which can provide insight into the chemical makeup of flowering plants. Headspace technology is a tool traditionally used in the fragrance industry to capture the makeup of plants at their aromatic peak. This is the first time the technology has been used for researching the cannabis plant.

All plants used in this study were grown in controlled conditions in a medical cannabis greenhouse. Researchers used Headspace tech to collect data from multiple top colas on the same plant to cut down the possibility for error. The study was focused on monitoring the patterns of terpene change throughout the cannabis life cycle in hopes of revealing the phytochemical difference between cured and live plant profiles.

The Headspace technology utilizes an adsorbent fiber located within a hollow glass dome to collect various volatile compounds from the live plant. Using this fiber, terpene content was collected at 3 stages: from fresh colas on the live plant, after they had been dried for one week, and again after being dried and cured.

The Results

As expected, the results offer insight into which terpenes degraded/evaporated and which preserved at various points of production from the farm to the dispensary shelf. Findings show that at the fresh, planted state, a cultivar has the highest expression of monoterpenes like Beta Myrcene, Alpha Pinene, Beta Pinene, and Limonene. After one week of drying and curing, each of these terpenes decreased significantly — Beta Myrcene content decreased by 55%. While monoterpenes were decreased during the curing process, sesquiterpenes like Alpha Humulene and Beta-Caryophyllene were increased. Sesquiterpenes almost doubled in their ratio from the total terpene content in data taken after the harvest processes were complete, with Alpha-Humulene increasing 100% and Germacrene increasing 154%.

A cannabis product may fail contaminant testing if it has unsafe levels of microbials, heavy metals or pesticides.

While cannabis has many beneficial properties for both medical and recreational users, it also comes with intrinsic dangers like mold and yeast.

Growing cannabis sometimes involves pesticides, and the water can be polluted.

Most states where cannabis is legal have enacted legislation that requires companies to pass tests before releasing their product on the market. This, in turn, created a problem for companies that must ensure their product is safe and compliant with all regulations.

Luckily, the demand for a pure cannabis spurred the development of decontamination technology.

Marijuana Really Helps You Poop, According to Science

Whether sprinkled in a spliff or used as papers for a blunt, tobacco has been marijuana’s closest companion for millennia. The interaction between the two substances seems to vary from person to person nearly as much as cannabis alone.

Anecdotally, people report a variety of interactions, with some people saying that tobacco smooths out their high, and others saying it provides a stimulating kick. As with cannabis itself, it is difficult to anticipate how a new user will react, due to the myriad chemical and psychological factors at play.

A Heady Combination

A major question in evaluating the cannabis-tobacco interaction is whether their effects are simply added together, or if the plants change one another. Spliffs are often the preferred consumption method for people who want to modulate their cannabis intake, but one study published in the research journal Inhalation Toxicology suggests that there may be a countervailing force: tobacco was found to increase THC intake by as much as 45 percent.

Studies of how cannabis and tobacco interact on one’s body and brain are out there, but the research is limited and the conclusions don’t venture much beyond associations and correlations. Regular blunt smoking is associated with greater cannabis dependence, as is the practice of chasing a joint with some nicotine. Tobacco has well-known addictive properties, and it’s not clear if smoking the two together makes one addicted to cannabis itself, or if the dependence is predominantly one on nicotine, with cannabis simply along for the ride.

Another study found that cannabis can satisfy a desire for tobacco, but not the other way around — specifically among people who smoke more than a joint a month, but fewer than three a week. Does that suggest that cannabis can substitute for tobacco, or just that spliff smokers are mostly in it for the weed, with tobacco thrown in for taste and a little extra buzz?

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Advertising and location of cannabis retailers influence adolescents’ intentions to use marijuana, according to a new study. The new study led by Washington State University researchers was published in the Journal of Health Communication. Stacey JT Hust, associate dean in the Murrow College of Communication, and Jessica Fitts Willoughby, associate professor of communication, conducted a survey of 13- to 17-year-old in Washington to find out how marijuana advertising and the location of marijuana retailers influence adolescents’ intentions to use the drug. The researchers also asked participants about their outcome beliefs--whether or not they thought using marijuana would be good for them personally and or socially. Their research shows regular exposure to marijuana advertising on storefronts, billboards, retailer websites and other locations increased the likelihood of adolescents using marijuana.

“While there are restrictions against using advertising designed specifically to target youth, it does still appear to be having some influence,” Willoughby said. “Our research suggests a need to equip adolescents with the knowledge and skills to critically evaluate marijuana advertisements.” The location of retail stores also played a role but the results of the survey were mixed. While the actual density of marijuana retailers in an area was not associated with adolescents’ intentions to use, study participants who said they lived within five miles of a marijuana shop were more likely to report intentions to use the drug than those who perceived they lived farther away.

“This was especially the case when they also reported having positive beliefs about marijuana use,” Hust said. “The study participants who felt positively about marijuana and perceived living close to retailers were the most likely to report intentions to use marijuana.” The results of the research team’s study could have significant policy implications as states that have legalised recreational marijuana use grapple with ways to adhere to the drug’s legal status while trying to prevent adolescent marijuana use.

For instance, most states with legalised marijuana restrict placing retailers and advertisements next to schools, but other locations, where adolescents live and spend a lot of their time, remain largely unregulated. “Our findings are particularly relevant given that most states that have legalised recreational marijuana have not restricted their proximity to neighbourhoods or living areas, which may be particularly challenging in large metropolitan areas,” Hust said. “States may want to consider using census data to identify the proportion of teens living in particular areas as they identify the location for marijuana retailers.”

The researchers are currently in the process of conducting a new experiment where they are testing different types of advertisements to see how young people interpret and respond to them. “One of the things this research and other studies suggest is that these advertisements are pretty prolific in certain areas and we want to see what type of appeals are used in the advertisements and how those appeals affect viewers,” Hust said. “Our long-term goal is really to develop a better understanding of how adolescents can make healthy and informed decisions in an environment in which marijuana is legal.”

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Many people around the world are discovering the benefits of medicinal cannabis. With its growing integration into modern medical practices, technology is also evolving to deliver greater quality and service to consumers.

From senior citizens to young adults with chronic health conditions, medical marijuana is a diverse industry that requires flexible, personal, and responsive technology. The emerging trends reflect increased legalization. As procedures change, the way people use technology to get medical marijuana will change. Here are some of the trends you can expect to see in the coming years.

Artificial Intelligence

Chatbots on websites will become more common as they help customers get answers to common questions and connect with important resources. AI will also be able to help customers search for different products, make personalized recommendations and perform a variety of customer service tasks. AI learns how to interact with people through every conversation; the more people use it, the smarter it becomes. Initial AI bots may seem clunky and mechanical, but as they become more widespread, users will eventually barely notice a difference between assistance from an AI and human.

From a business standpoint, AI will also begin to be used to automate more operations. AI is capable of monitoring growth and synthesizing information at a rate no human could ever match; higher demand for medical marijuana will require faster production. AI reduces the margin of error to ensure the cannabis remains safe despite

DNA Sequencing

New DNA technology will create a more regulated cannabis industry, including medical marijuana products that contain not even trace amounts of THC or CBD. Growers will then be able to customize or strengthen the medicinal benefits to suit people’s needs and serve a greater audience. Extracting genes and creating new types will pave the way for unprecedented evolutionary growth and use of the plant. With the ability to deconstruct, extract, and modify, there may eventually be a new type of manufacturing that replicates the compounds of medical marijuana without actually requiring a plant.

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For many who choose to live and work in Northern Colorado’s agricultural communities, there’s more to love than just the picturesque mountains in the distance or the easy accessibility to major metropolitan hubs like Denver and Fort Collins.

The area provides access to ag-based educational opportunities, industry partnerships, and processing facilities that just aren’t available in many parts of the country.

Creating a Knowledge Base

Owner of Hemp Processing Partners Shane Pritchard is opening an industrial hemp collaboration hub and laboratory in Greeley later this year.

He explained why the area is such an ideal fit: “Greeley and Weld County are very strong agricultural areas and we have access to agricultural universities, with Colorado State University in Fort Collins, the University of Northern Colorado in Greeley, and Aims Community College. So there are good educational resources there and a lot of really productive agricultural land.”

Hemp Ventures is a hemp processing and technologies company led by CEO Ryan Doherty.

The largest wildfire in the history of California, the August Complex, is still burning.

It has scorched more than a million acres in Northern California and is threatening three counties, Mendocino, Humboldt and Trinity, that have the largest concentration of cannabis farms in the U.S., reports Inside Climate News.

According to local law enforcement officials, many growers have defied evacuation orders to stay behind and protect their crops and livelihoods.

As California cycles though wildfires and droughts with increasing intensity and severity, cannabis farmers and the medical patients they serve, are under threat.

“Fires are just a way of life at this point,” David Najera, a cannabis farmer in Mendocino County, recently told The Source. “We’ve already broken the record for most acres burned in history, and we haven’t even gotten to the worst part of the season,” Najera said.

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Measure 110 would reduce all drug possession arrests to misdemeanors and cause all drug convictions to drop by 91%.

Facebook founder Mark Zuckerberg and his wife Priscilla Chan have put their weight behind a measure to decriminalize all drugs in Oregon. The couple contributed $500,000 to the campaign, which would also earmark a significant amount of state cannabis tax revenue toward substance abuse treatment.

Measure 110, the ballot item in question, aims to change the narrative around drug use in the state. Instead of treating drug users as criminals, campaign organizers believe substance abuse should be treated as a public health issue.

“The war on drugs has created stereotypes and misinformation about people who are addicted to drugs and people who use drugs and made it easy to make it afraid of people who use drugs,” Yes on 110 campaign manager Peter Zuckerman told The Willamette Week. “Our biggest obstacle is the stigma.”

The Facebook couple became the second biggest financial backers of Measure 110 with their donation, made through their Chan Zuckerberg Initiative Advocacy. Drug Policy Action, an advocacy organization under the Drug Policy Alliance, contributed around $2.5 million when the campaign was gathering signatures to qualify for the polls, The Oregonian reports. Since making it on the ballot, Drug Policy Action made a $862,000 to raise voter awareness about the measure.

Mark Zuckerberg Donates $500K To Decriminalize All Drugs in Oregon

Cannabis in cosmetics is becoming a big thing all over the world, but what laws are there to govern the industry, and which parts of the plant can be used?

Much like nearly everything else pertaining to cannabis, different locations have their own specifications. In the US, for example, the FDA has made no official move to set regulatory standards for cannabis in cosmetics, though it has been spending time trying to get a handle on CBD in general. As of the last farm bill, industrial hemp with THC amounts of up to .3% is legal for industrial use, with some gray area over the use of cannabinoid preparations, which still mainly remain illegal.

When looking at regulation for something like cannabis in cosmetics, there are two main factors to consider: 1) the THC content, since nearly all cannabis cosmetics will be focused around CBD, and 2) which part of the plant is used for the raw materials, as some countries have different stipulations here.

Cannabis Cosmetics in the US of A

An important thing to understand about the US is that the FDA, under the FD&C Act, isn’t required to approve cosmetic products or ingredients, with the exception of many color additives, and any substance that is prohibited or restricted otherwise.

In fact, most people have probably already noticed the message found on many herbal products that says “These statements have not been evaluated by the Food and Drug Administration.” The products they’re found on aren’t illegal, just simply not under regulation by the FDA, or legally requiring of it.

As of right now, no cannabis, or cannabis-derived ingredients, are specifically banned from cosmetics as they are not specifically addressed by the law. This doesn’t mean that such products get out of being up to code for all other requirements and regulations, even if not specifically mentioned.

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With the lockdown restrictions easing, COVID-19 remains a very serious health threat worldwide. Dozens of coronavirus vaccines are in development across the world in combined global effort with high hopes to bring one to the market in record time to ease the global crisis.

One interesting candidate is cannabidiol or CBD. Recent research shows it may help fight COVID-19.

What the research says

According to a study conducted at the University of Lethbridge in Alberta, Canada, those with raised CBD levels could reduce the adverse effect of coronavirus on the human body by examining hundreds of cannabis strains. Cannabis Sativa strains are high in CBD, and scientists could develop this core cannabis component to develop preventative treatments such as mouthwash products for both clinical and home use.

The research was carried out by Drs. Olga and Igor Kovalchuk, professors at the University of Lethbridge’s Department of Biological Sciences, along with researchers from Pathway RX, under a research license from Health Canada at the University of Lethbridge, which continues to actively pursue partnerships to conduct clinical trials.

Results from the study show that that hemp extracts high in CBD could potentially act as a barrier against the protein that provides a gateway in certain tissues for COVID-19 to enter host cells by balancing levels of angiotensin-converting enzyme II (ACE2). The virus can enter the host cells via ACE2, and inflecting those levels in the lung, kidney, gastrointestinal tract, nasal mucosa, and testes would reduce the host's susceptibility to COVID-19 significantly.

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Despite the recent success of low-THC cannabis flowers, there are still many skeptics of the smokable hemp “fad.” Many of these critics fail to distinguish between industrial-grade and premium high-CBD smokable hemp. Examined closely, there is a world of difference in flower quality between these two hemp variants.

Put bluntly, industrial hemp is grown for mass not quality. Therefore farmers produce industrial hemp for…well, industrial purposes. From plastic and paper to concrete and car fuel, hemp has many uses across various sectors. So understandably industrial farmers are most concerned with producing plants that yield the highest quantity of hemp imaginable for those purposes.

But when hemp is produced for human consumption, professional cultivators are more concerned with producing the highest quality hemp flower for a growing number of consumers. Unlike tightly-packed industrial hemp fields, expert cultivators give high-CBD hemp the space required to grow profound buds with complex and fragrant aromatics. Essentially, hemp flower is being cultivated with all of the same care and attention of it’s higher THC cousins. Online companies like Cannaflower’s are forging a whole new low THC market for cannabis consumers in all 50 states with buds that impress on the eyes and the nose every bit as much as medical grade cannabis. 

Although hemp is often associated with its industrial uses, it’s important to remember that botanists didn’t create the term “hemp.” Indeed, the distinction between “hemp” and “marijuana” is primarily a matter of legalese. Essentially, the genetics all come from 

By law, hemp must contain less than 0.3 percent THC. But in reality, both marijuana and hemp are cannabis plants where when professional farming techniques are applied, produce high-quality buds.

The fake cannabinoids are coming. And, like the artificial meat popping up on fast-food menus and grocery shelves across the country, they could disrupt multiple industries.

As CBD has become more popular, a growing number of companies are scaling up efforts to produce lesser-known cannabinoids such as CBG and CBN. Although the compounds can come from the plant itself, some biotech firms are finding it’s cheaper to engineer them synthetically.

Now, the race is on to improve production and bring down costs as demand grows for cannabis-derived treatments for sleep, pain relief, relaxation and more. That could open new opportunities for consumer goods and pharmaceuticals.

While CBD has gotten all the attention lately -- with help from big names like Martha Stewart, who recently launched gummies, and Molson Coors Beverage Co., which has a partnership for CBD drinks -- more than 100 other compounds can be extracted. As consumers familiarize themselves with the alphabet soup of options, one increasingly popular one is cannabigerol, or CBG, which is used to treat pain and nausea -- and, like CBD, doesn’t have the psychoactive effects of THC.

Willow Biosciences said last month that it’s working with manufacturer Albany Molecular Research to achieve large-scale production of CBG by the middle of next year. Willow, based in Calgary, Alberta, sold out of its first batch of the compound, and about 17 more companies have said they want to buy the next samples when they become available, said Chief Executive Officer Trevor Peters.

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Love strain-specific edibles but have a hard time finding them? You are not alone! As people learn more about the variety present in cannabis’ many strains, many find that only some of these options give them the effects they are looking for. For those strain-sensitive patients who prefer edibles, this can present a challenge. It’s not always easy to find the strains you need locally, but it can be almost impossible to find them in edibles. Since most edible companies leave the strain a mystery (or mix many strains together) it is hard to find specific strains when you need them.

Making edibles at home is a great way to bypass the problem but edible recipes can get complicated. Most people don’t want to labor over a pot for hours, constantly checking that the temperature is still in the perfect zone. If you have had a hard time making edibles at home, here are five shortcuts simplify this tasty task:

Use a Magical Butter Machine

Edible bases can be tricky to make, and usually involve a long infusing process where the temperature needs to be just right. The Magical Butter machine really simplifies this process. You put your decarboxylated marijuana and your butter into the machine and push a button. Two hours later, your perfectly infused butter is ready to go. Since it can help make many common bases like butter, oil, glycerin, honey, and alcohol, the Magical Butter machine can simplify almost any edible recipe.

Cook the Weed Right In

Infused oils aren’t the only way to make an edible. If you want to skip the process of making a base and get right to making your edibles, try these recipes that use the flower itself. Do you ever vape your favorite strains? This delicious pesto recipe turns the left over flower in your vape into a culinary experience. Or try turning your cannabis into canna-flour, with this zucchini bread recipe. The recipe teaches you how to grind up your preferred pot into a powdered form that can be baked right into your favorite treats.

Eat it Fresh

You can skip the cooking altogether by eating raw cannabis fan leaf. This not only simplifies your process, but you can also gain the benefits of the plant’s unaltered natural compounds like THCA. The most popular method for consuming the raw plant is juicing it. The juice can be mixed with other fruit or veggie juices for flavor and can be frozen in ice trays to preserve for later. Still, some skip the juicing all together and put the leaf straight into their salad. The high is fairly different from infused and decarboxylated edibles so you might also find that different strains work well for you fresh than when consumed other ways.

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These encouraging results indicate medicinal cannabis can help improve quality of life for chemotherapy patients.

Tilray, Inc. (NASDAQ: TLRY) announced that Australian researchers have published preliminary results finding that one of the company’s GMP-produced products is showing promise reducing nausea and vomiting for cancer patients undergoing chemotherapy in a clinical trial.

The results were published in the Annals of Oncology which found a significant improvement in the control of chemotherapy-induced nausea and vomiting. A quarter of the patients taking medicinal cannabis experienced no vomiting and nausea, compared to 14 percent of people who took a placebo. The pilot phase of the study ran for two-and-a-half years with 81 participants enrolled. To be included in the study, patients had to have already experienced nausea and vomiting during chemotherapy despite having taken nausea prevention medication.

“The side-effects associated with chemotherapy are some of the primary causes of treatment discontinuation”, says Philippe Lucas, Vice President of Global Patient Research and Access at Tilray, “so improving the control of nausea and vomiting can not only improve the quality of life of patients but by allowing those affected by cancer to complete their treatment it can also potentially save lives.”

While cannabis has been used before as a remedy for chemo nausea, the most prescribed medicine is Marinol, which is owned by the biotech company AbbVie (NASDAQ: ABBV). However, Marinol is a synthetic drug and patients typically quit renewing their prescriptions based on the side effects and general displeasure with the drug.

Wearing hemp clothing is no longer a fringe, hippie fashion statement. In fact, big brands and high end boutiques alike are embracing the sustainable material.

Levi’s and Nike have both recently released ranges made of hemp. While Levi’s has long been the leader in denim, they’ve admitted their products aren’t the most eco-friendly, with the production of a pair of jeans and a t-shirt requiring approximately 20,000 litres of water. Using cottonised hemp and their patented “Water

In a time marked by shuttered business, depressed consumer shopping, and plunging retail spending, not many markets can claim the victory that the CBD (cannabidiol) market has done so far. Back in 2018, sales of CBD products in the United States alone harvested a generous $600 million-$2 billion. Sales of CBD have actually grown slightly from those impressive numbers in 2019, as more consumer concerned about their health have switched their shopping habits, and now buy full-spectrum CBD online directly from the manufacturers. This is according to a report published by Forbes, which also foresees the figure inflating upwards of $16 billion by 2025.

As a cannabis-derived compound that harbors numerous pharmacological actions, such as antiemeticanti-inflammatoryanxiolytic and antipsychotic properties, it is understandable why the market has such promising prospects. 

While emerging research is highlighting the benefits of this non-psychotropic cannabinoid, a handful of studies have also spotlighted how CBD lacks the non-toxic properties to cause negative changes on food intake, blood pressure, body temperature, heart rate, gastrointestinal transit, psychomotor and psychological functions.

But just how safe is it and should you be wary of introducing CBD into your lifestyle? Read on to find out.

CBD Research Has Been Suffocated by Classification Standards 

Due to the Drug Enforcement Administration (DEA) classifying the cannabis plant as an illegal substance since the 1970s, strict restrictions have been imposed on CBD research for the past decade. Anyone who wishes to study the plant-derived compound is welcome to do so, buy only if they have obtained the necessary license.

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Buying CBD products can be confusing to say the least. One thing that often perplexes CBD consumers is the difference between broad spectrum and full spectrum CBD.

With thousands of CBD products on the market, different brands are struggling to stand out. One major difference between CBD oil tinctures is whether they contain broad spectrum or full-spectrum CBD. It doesn’t help that products are also frequently mislabeled, too.

In brief, the hemp plants has hundreds of natural chemicals in it, including the “cannabinoids” that cause its beneficial effects. The most well known cannabinoids are CBD, the popular supplement, and THC, which is the main “active” ingredient in psychoactive cannabis (a.k.a. “marijuana”). But many other cannabinoids exist.

Both broad spectrum and full spectrum CBD products contain a variety of these natural cannabinoids, but differ in one key ingredient. While neither type of CBD will make you “feel high,” full spectrum CBD has tiny amounts of THC in it while broad spectrum doesn’t have any at all.

But there’s a lot more to learn, so read on to understand more about the different types of CBD oil and why it could matter to you.

A dropper of broad spectrum CBD oil held over a drinking glass of water, with droplets falling into a beverage.

Resource Innovation Institute Executive Director Derek Smith highlights the importance of tracking resource consumption in cannabis production.

As the global COVID-19 pandemic provides a window into cannabis’s increasing revenue potential, the industry’s Achilles heel on production scalability is being laid bare. Global brands with cultivation assets in various parts of the world are generally incapable of achieving consistent quality from site to site – and their stock prices reflect it.

Saddled with high operating expenses resulting from hasty decisions on geographies, building types, lighting solutions and heating, ventilation and air conditioning (HVAC) systems, executives are forced to identify cuts, yet have very limited ways to assess the operating capabilities of their master growers. With energy and water costs comprising up to 50% of total operating expenses, resource efficiency is paramount.

At the same time, savvy investors with experience in more mature sectors are beginning to concern themselves with Environment, Social and Governance (ESG) performance; and, of course, consumer interest in corporate action on climate change and other pressing social and environmental matters is on the rise.

What gets measured gets done

All of this points to the urgent need for producers to become more operationally efficient. In order to begin a journey down the efficiency path, a producer must first know how efficient their operation already is. From this, they can establish a baseline from which to measure and report performance.

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Cannassure Therapeutics Ltd (TASE: CSURE) (“Cannassure”), an Israel based developer and producer of innovative medical cannabis products, announces today the successful completion of a feasibility study for the development of IP protected, homogeneous, topical medical Cannabis products for the treatment of skin inflammation, including psoriatic lesions. (PRESS RELEASE)

Product development of such topical medical Cannabis products based on AKVANO® is being conducted under a collaboration between Cannassure and Lipidor AB (“Lipidor”), a Swedish topical drug development company, owner of the proprietary drug delivery platform technology AKVANO, which was signed in December 2019. The development project budget is partially funded by the Israeli Innovation Authority, by a non-dilutive grant.

The product under development is an incorporation of cannabinoids with AKVANO®, a topical drug delivery platform. Successful development of the product will allow localized administration of a precise dosage of cannabinoids using a spray, in a technology that allows for prolonged contact and optimal penetration of the active ingredient into the skin.

As part of the feasibility study, AKVANO® technology and cannabinoids were tested for compatibility, and it was found that the cannabinoids can be successfully combined in the AKVANO® system for a homogeneous, uniform and stable formulation. Cannassure tested the degree of product penetration into the skin by using known and acceptable models and found significant penetration of active ingredients into the skin tissue. This enhanced penetration may increase the therapeutic potential of the product. Based on these results, Cannassure will proceed to accelerated development stages and more advanced testings.

According to the agreement, Cannassure has informed Lipidor on its intention to start negotiating an exclusive global license for the use of Lipidor’s technology for the development of cannabinoids based topical therapeutics products for the treatment of indications to be chosen by Cannassure.